Biomedical Research & Innovation Platform Symposium 2019, SAMRC Conference Centre, 21 October 2019

The organizing committee takes great pleasure in welcoming you to the 9th annual BRIP Symposium. A special welcome to The President and CEO of the SAMRC. A special thank you to our guest speakers for availing their time and sharing their expertise with us. We also look forward to the post-graduate student presentations showcasing their research. We hope that the symposium encourages scientific dialog and interaction between these young scientists and established scientists visiting us from various universities and other research units. Thank you to Prof Jeffrey Mphahlele sponsoring the prizes for the best presentations. Your participation and support are greatly appreciated.

Wishing alI a fantastic meeting
Best wishes,

Scientific Programme & Abstracts

Guest Speakers

Professor Bernd Rosenkranz

(Stellenbosch University/ Fresenius University of Applied Sciences Faculty of Economics & Media, Germany)


Prof Emeritus Bernd Rosenkranz has a medical degree and a board-certified Pharmacologist and Clinical Pharmacologist in Germany and South Africa. He is also a Fellow of the Faculty of Pharmaceutical Medicine (FFPM).  He has spent 23 years in industry, as Director of Clinical Pharmacology at Hoechst/Hoechst Marion Roussel in Germany, France and USA, Chief Medical Officer at 3 Clinical Research in Berlin, Germany, and Vice President Clinical Development at Jerini, Berlin, Germany. From 2008 until 2016, Prof Rosenkranz was a Professor/Chief Specialist in Pharmacology and head of the Division of Clinical Pharmacology, Stellenbosch University, where he established the postgraduate programme in Pharmaceutical Medicine / Medicines Development (PharmaTrain Centre of Excellence). Since 2017, he has been a lecturer at the Fresenius University of Applied Sciences Faculty of Economics & Media, Germany. Prof Rosenkranz is also a President of the Fundisa African Academy of Medicines Development, board member and Honorary Member of the South African Society for Basic and Clinical Pharmacology (SASBCP), and affiliate of the College of Clinical Pharmacologists (CMSA). He is a member of the International Federation of Associations of Pharmaceutical Physicians and Pharmaceutical Medicine (IFAPP), the European PharmaTrain Federation, and the PharmaTrain Certification Board for the Specialist in Medicines Development programme. He was a Chair of the South African Congress of Pharmacology and Toxicology (SACPT 2010), and the Finance Committee of the 17th World Conference of Basic and Clinical Pharmacology (WCP2014), currently Prof Rosenkranz is a finance Chair of the 3rd World Conference on Pharmacometrics (WCoP2020, to be held in Cape Town, South Africa during the 6-9 April 2020). He is a peer reviewer for several journals, reviewer for the NRF and external examiner at several Universities in South Africa. His work has been presented in more than 110 original publications, 17 book chapters, and more than 170 oral or poster presentations. Prof Rosenkranz is an Associate Editor of Frontiers in Pharmaceutical Medicine and Outcomes Research and a vice treasurer of the Manenberg Aftercare Centre, Cape Town.

Professor Luca Tiano

(Polytechnic University of Marche, Ancona, Italy)


Prof Tiano is a researcher at the Department of Clinical Sciences at the Polytechnic University of Marche, Ancona, Italy. His main research activities concern the health effects of lipophilic cofactors (Coenzyme Q10 and Vitamin K) in healthy subjects and under pathological conditions associated with enhanced oxidative stress. He has been in research on bioavailability and biological effects of vitamins and antioxidants in nutritional supplements and functional foods. Prof Tiano has also been involved in research on oxidative stress and the use of antioxidants in cellular or in vivo models both under physiological conditions or in pathologies associated with an altered redox status since 1997. During his Ph.D. training in Biochemistry at the University of Camerino (1997-2001) he utilized models of oxidative DNA damage and mitochondrial dysfunction involving fish erythrocytes to test the protective effects of natural and synthetic antioxidants. Moreover, he has been involved in eco-toxicological research regarding oxidative damage induced by environmental xenobiotics. Within this area of research Prof Tiano was selected to conduct a European Community research project at the Marie Curie Training Site held by The University of Aberdeen and FRS, in Scotland. He is involved in joint research projects with Children’s Hospital, Salesi and the Heart Institute, Lancisi. Prof Tiano is an Associate Professor in Biochemistry since 2016, at the Department of Life and Environmental Sciences, Polytechnic University of Marche. These research activities have seen the active collaboration with biotechnology industries (Kaneka, Gnosis), food supplement industries (Jarrow Formulas, Pharmanord), food companies (Parmalat, Oleificio Costa d’oro, Latterie Merano) Cosmetic and pharmaceutical companies (Angelini, Beiersdorf). Prof Tiano teaches Biochemistry, Nutrigenetics, and also focus on Oxidative stress in Biological systems at the Department of Life and Environmental Sciences, UNIVPM. Prof Tiano has active academic collaborations previously funded with three years grant by the Italian Ministry of Foreign Affairs with the South African Medical Research Council (Prof. C. Muller) and a collaboration with the Institute of Myology, Université Pierre et Marie Curie, Paris 6 (Prof. G. Butler-Browne) funded by the France Ambassy in Italy. He is author of 95 papers on international peer-reviewed journals (H factor 24, Cit 2046). He is on the board of the European Society of Comparative Biochemistry and Physiology and Executive Committee Member of the International Coenzyme Q10 Association.

Dr Silvestri Sonia

(Polytechnic University of Marche, Ancona, Italy)


Dr  Sonia Silvestri graduated in Food and Nutrition Sciences at the Politechnic University of Marche (2010) and PhD in Biological and Clinical Sciences at the Faculty of Medicine of Politechnic University of Marche (2016), Her thesis on “Molecular mechanisms involved in sarcopenia during aging” focused on the molecular mechanism involved in the senescence process of skeletal muscle. During her last year of PhD, Dr Silvestri spent four months at the Myology Institute, Sorbonne University of Paris, to deepen her knowledge in the field of cellular biology, in particular studying the effect of statin on oxidative stress in skeletal myocytes. This project was supported by a scholarship of the “Ambassade de France en Italie”, in order to encourage the scientific research exchange between France and Italy. In 2017 and 2019 she was awarded with two yearly scholarships funded by Veronesi Foundation. In the first year, she evaluated the efficacy of dietary supplementation with ubiquinol in association with exercise training, to assess whether nutritional intervention in the elderly could contribute to an enhanced adaptive response. Presently, within the second grant, she’s evaluating the antitumor activity of organometallic ruthenium (II) arene anticancer complex alone or in association with monoterpene d-limonene. She focused mainly on oxidative stress in biological systems induced by different drugs such as simvastatin and antitumor compounds using animal, muscle and breast cancer cell culture models. Results from her research contributed to the production of 20 scientific articles in international peer-reviewed journals in the field of biochemistry, physiology and nutrition.


Monday, October 21, 2019 - 08:15 to 17:45