COVID-19 forecasts

Cases and deaths predictions based in data driven modeling - click to open
Additional detail regarding modelling approach
Phenomenological models have previously been applied to model disease outbreaks such as Ebola (Pell et al., 2018), Zika virus (Sebrango-Rodríguez et al., 2017) and more recently the COVID-19 outbreak (Roosa et al., 2020; Shen, 2020). We adopt a similar approach to model the COVID-19 trajectory in South Africa. Specifically, the logistic growth model, Richards model, Weibull model and Gompertz model are calibrated to the reported number of COVID-19 cases and deaths from 5 March 2020 to present, and predictions are presented for the models which provide the best fit to the data. The aforementioned models are fitted using least squares estimation. We rely on the general bootstrap method (Efron & Tibshirani, 1994) and apply a parametric bootstrapping approach which has used previously to quantify parameter uncertainty and construct confidence intervals in modeling studies(Chowell, 2017; Chowell et al., 2019) . In this method, multiple observations are repeatedly sampled from the best-fit model to quantify parameter uncertainty by assuming that the time series follows a Poisson distribution.

References

  • Chowell, G., 2017. Fitting dynamic models to epidemic outbreaks with quantified uncertainty: A primer for parameter uncertainty, identifiability, and forecasts. Infect. Dis. Model. 2, 379–398.
  • Chowell, G., Tariq, A., Hyman, J.M., 2019. A novel sub-epidemic modeling framework for short-term forecasting epidemic waves. BMC Med. 17, 164.
  • Pell, B., Kuang, Y., Viboud, C., Chowell, G., 2018. Using phenomenological models for forecasting the 2015 Ebola challenge. Epidemics 22, 62–70.
  • Roosa, K., Lee, Y., Luo, R., Kirpich, A., Rothenberg, R., Hyman, J.M., Yan, P., Chowell, G., 2020. Short- term Forecasts of the COVID-19 Epidemic in Guangdong and Zhejiang, China: February 13-23, 2020. J. Clin. Med. 9, 596.
  • Sebrango-Rodríguez, C.R., Martínez-Bello, D.A., Sánchez-Valdés, L., Thilakarathne, P.J., Del Fava, E., Van Der Stuyft, P., López-Quílez, A., Shkedy, Z., 2017. Real-time parameter estimation of Zika outbreaks using model averaging. Epidemiol. Infect. 145, 2313–2323.
  • Shen, C.Y., 2020. Logistic growth modelling of COVID-19 proliferation in China and its international implications. Int. J. Infect. Dis. 96, 582–589.