Profiling Science

SAMRC’s COVID-19 research, funding and innovations - Video
SAMRC Jerusalema Challenge
Researchers are calling for greater regulation of the alcohol industry
COVID-19 Research
Metformin and heart failure–related outcomes in patients with or without diabetes: a systematic review of randomized controlled trials
Dludla PV, Nyambuya TM, Johnson R, Silvestri S, Orlando P, Mazibuko-Mbeje SE, Gabuza KB, Mxinwa V, Mokgalaboni K, Tiano L, Muller CJF, Louw J, Nkambule BB.
Exploring the comparative efficacy of metformin and resveratrol in the management of diabetes-associated complications: a systematic review of preclinical studies
Dludla PV, Silvestri S, Orlando P, Gabuza KB, Mazibuko-Mbeje SE, Nyambuya TM, Mxinwa V, Mokgalaboni K, Johnson R, Muller CJF, Tiano L, Louw J, Nkambule BB.
Recent developments with advancing gene therapy to treat chronic infection with hepatitis B virus
Maepa MB, Jacobs R, van den Berg F, Arbuthnot P
Health workers’ perceptions and experiences of using mHealth technologies to deliver primary healthcare services: a qualitative evidence synthesis
Odendaal WA, Leon N, Goudge J, Griffiths F, Tomlinson M, Daniels K
Maternal and infant outcomes among pregnant women treated for multidrug/rifampicin-resistant tuberculosis in South Africa
Loveday M, Hughes J, Sunkari B, Master I, Hlangu S, Reddy T, Chotoo S, Green N, Seddon JA
Mycobacterium tuberculosis and myeloid-derived suppressor cells: Insights into caveolin rich lipid rafts
Kotzé LA, Young C, Leukes VN, John V, Fang Z, Walzl G, Lutz MB, du Plessis N
Novel techniques for detection of mycobacterium bovis infection in a cheetah
Kerr TJ, Gumbo R, Goosen WJ, Rogers P, Last RD, Miller MA
Dihydrocodeine for detoxification and maintenance treatment in individuals with opiate use disorders
Carney T, van Hout MC, Norman I, Dada S, Siegfried N, Parry CDH
A landscape of genomic alterations at the root of a near-untreatable tuberculosis epidemic
Klopper M, Heupink TH, Hill-Cawthorne G, Streicher EM, Dippenaar A, de Vos M, Abdallah AM, Limberis J, Merker M, Burns S, Niemann S, Dheda K, Posey J, Pain A, Warren RM.
Xpert MTB/RIF Ultra and Xpert MTB/RIF for diagnosis of tuberculosis in an HIVendemic setting with a high burden of previous tuberculosis: a two-cohort diagnostic accuracy study
Mishra H, Reeve BWP, Palmer Z, Caldwell J, Dolby T, Naidoo CC, Jackson JG, Schumacher SG, Denkinger CM, Diacon AH, van Helden PD, Marx FM, Warren RM, Theron G.
Mental, behavioral and neurodevelopmental disorders in the ICD-11: an international perspective on key changes and controversies
Stein DJ, Szatmari P, Gaebel W, Berk M, Vieta E, Maj M, de Vries YA, Roest AM, de Jonge P, Maercker A, Brewin CR, Pike KM, Grilo CM, Fineberg NA, Briken P, Cohen-Kettenis PT, Reed GM.
Immunogenicity and safety of different dosing schedules of trivalent inactivated influenza vaccine in pregnant women with HIV
Nunes MC, Cutland CL, Moultrie A, Jones S, Ortiz JR, Neuzil KM, Klugman KP, Simões EAF, Weinberg A, Madhi SA, Hugo A, Sithole P, Stoltenkamp LA, Abdoola Y, van Niekerk N, Treurnicht F.
Expanding our understanding of the triglyceride paradox in populations of African ancestry
Goedecke JH
Structural determinants of gender inequality: why they matter for adolescent girls' sexual and reproductive health
George AS, Amin A, De Abreu Lopes CM, Ravindran TKS
Careful governance of African biobanks
Christoffels A, Abayomi A
Process elements contributing to community mobilization for HIV risk reduction and gender equality in rural South Africa
MacPhail C, Khoza N, Treves-Kagan S, Selin A, Gómez-Olivé X, Peacock D, Rebombo D, Twine R, Maman S, Kahn K, DeLong SM, Hill LM, Lippman SA, Pettifor A.
Immunogenicity and safety of fractional dose yellow fever vaccination: a systematic review and meta-analysis
Nnaji CA, Shey MS, Adetokunboh OO, Wiysonge CS.
Liver is widely eaten by preschool children in the Northern Cape province of South Africa: implications for routine vitamin A supplementation
van Stuijvenberg ME, Schoeman SE, Nel J, le Roux M, Dhansay MA.
Service providers perceptions of barriers to the implementation of trauma-focused substance use services for women in Cape Town, South Africa
Myers B, Carney T, Johnson K, Browne FA, Wechsberg WM.
Negative association of interleukin-33 plasma levels and schistosomiasis infection in a site of polyparasitism in rural Cameroon
Kamdem SD, Konhawa F, Kuemkon EM, Meyo Kamguia L, Tchanana GK, Nche F, Oumarou A, Hamza M, Ouratou Y, Tcheutchoua MN, Ghislain Essomba R, Ngogang MP, Kengne M, Netongo PM, Ondigui BE, Okomo Assoumou MC, Brombacher F, Nono JK
The gut microbiome in tuberculosis susceptibility and treatment response: guilty or not guilty?
Eribo OA, du Plessis N, Ozturk M, Guler R, Walzl G, Chegou NN
Therapeutic host-directed strategies to improve outcome in tuberculosis
Young C, Walzl G, Du Plessis N
Strengthening quality of care for children who are HEU
Goga A.
Effect of co-trimoxazole prophylaxis on morbidity and mortality of HIV-exposed, HIV-uninfected infants in South Africa: a randomised controlled, non-inferiority trial
Daniels B, Coutsoudis A, Moodley-Govender E, Mulol H, Spooner E, Kiepiela P, Reddy S, Zako L, Ho N, Kuhn L, Ramjee G.
Mycobacterium tuberculosis: concentrate resources on recent infections.
van Helden PD, Hoal EG.
An observational pilot study evaluating the utility of minimally invasive tissue sampling to determine the cause of stillbirths in South African women
Madhi SA, Pathirana J, Baillie V, Cutland C, Adam Y, Izu A, Bassat Q, Blau DM, Breiman RF, Hale M, Johnstone S, Martines RB, Mathunjwa A, Nzenze S, Ordi J, Raghunathan PL, Ritter JM, Solomon F, Wadula J, Zaki SR, Chawana R.
Unraveling specific causes of neonatal mortality using minimally invasive tissue sampling: an observational study
Madhi SA, Pathirana J, Baillie V, Izu A, Bassat Q, Blau DM, Breiman RF, Hale M, Mathunjwa A, Martines RB, Nakwa FL, Nzenze S, Ordi J, Raghunathan PL, Ritter JM, Solomon F, Velaphi S, Wadula J, Zaki SR, Chawana R.
Potential of minimally invasive tissue sampling for attributing specific causes of childhood deaths in South Africa: a pilot, epidemiological study
Chawana R, Baillie V, Izu A, Solomon F, Bassat Q, Blau DM, Breiman RF, Hale M, Houpt ER, Lala SG, Martines RB, Mathunjwa A, Nzenze S, Pathirana J, Petersen KL, Raghunathan PL, Ritter JM, Wadula J, Zaki SR, Madhi SA.
High rates of drug-induced liver injury in people living with HIV coinfected with Tuberculosis irrespective of antiretroviral therapy timing during antituberculosis treatment: results from the starting antiretroviral therapy at three points in TB trial
Naidoo K, Hassan-Moosa R, Mlotshwa P, Yende-Zuma N, Govender D, Padayatchi N, Abdool-Karim SSS.
Time to strengthen HIV treatment and prevention for youth
Pettifor A, Filiatreau L, Delaney-Moretlwa S.
HIV incidence rates in adolescent girls and young women in sub-Saharan Africa
Karim SSA, Baxter C.
Social media and HPV vaccination: unsolicited public comments on a Facebook post by the Western Cape Department of Health provide insights into determinants of vaccine hesitancy in South Africa
Wiyeh AB, Cooper S, Jaca A, Mavundza E, Ndwandwe D, Wiysonge CS.
Factors that influence acceptance of human papillomavirus (HPV) vaccination for adolescents: a qualitative evidence synthesis
Cooper S, Schmidt BM, Ryan J, Leon N, Mavundza E, Burnett R, Tanywe AC, Wiysonge CS.
Progression to type 2 diabetes mellitus and associated risk factors after hyperglycemia first detected in pregnancy: a cross-sectional study in Cape Town, South Africa
Chivese T, Norris SA, Levitt NS.
Immune correlates of the Thai RV144 HIV vaccine regimen in South Africa.
Gray GE, Huang Y, Grunenberg N, Laher F, Roux S, Andersen-Nissen E, De Rosa SC, Flach B, Randhawa AK, Jensen R, Swann EM, Bekker L-G, Innes C, Lazarus E, Morris L, Mkhize NN, Ferrari G, Montefiori DC, Shen X, Sawant S, Yates N, Hural J, Isaacs A, Phogat S, DiazGranados CA, Lee C, Sinangil F, Michael NL, Robb ML, Kublin JG, Gilbert PB, McElrath MJ, Tomaras GD, Corey L.
The Lancet Respiratory Medicine Commission: 2019 update: epidemiology, pathogenesis, transmission, diagnosis, and management of multidrug-resistant and incurable tuberculosis
Dheda K, Gumbo T, Maartens G, Dooley KE, Murray M, Furin J, Nardell EA, Warren RM, The Lancet Respiratory Medicine drug-resistant tuberculosis Commission group.
Participation of traditional, complementary and alternative health practitioners in conventional health systems in low‐ and middle‐income countries
Street R, Falkenberg T, Sundberg T, Balakrishna Y, Abrams A, Kredo T.
Breastfeeding, HIV exposure, childhood obesity, and prehypertension: a South African cohort study
Houle B, Rochat TJ, Newell ML, Stein A, Bland RM.
Tuberculosis diagnosis in children using Xpert ultra on different respiratory specimens
Zar HJ, Workman LJ, Prins M, Bateman LJ, Mbhele SP, Whitman CB, Denkinger CM, Nicol MP.
Unmasking the vulnerabilities of uninfected children exposed to HIV
Ramokolo V, Goga AE, Slogrove AL, Powis KM.
Obsessive-compulsive disorder
Stein DJ, Costa DLC, Lochner C, Miguel EC, Reddy YCJ, Shavitt RG, van den Heuvel OA, Simpson HB.
Validations of verbal autopsies - Comment on 'automated versus physician assignment of cause of death for verbal autopsies: Randomized trial of 9374 deaths in 117 villages in India'
Garenne M.
Improving outcomes in patients with non-tuberculous mycobacterial disease: is there light at the end of the tunnel?
Dheda K.
Management of active tuberculosis in adults with HIV
Meintjes G, Brust JCM, Nuttall J, Maartens G.
Differential burden of peripheral artery disease
Kengne AP, Echouffo-Tcheugui JB.
Harnessing biological insight to accelerate tuberculosis drug discovery
de Wet TJ, Warner DF, Mizrahi V.
Trends, patterns and determinants of long-acting reversible methods of contraception among women in sub-Saharan Africa
Adedini SA, Omisakin OA, Somefun OD.
A cross sectional analytic study of modes of delivery and caesarean section rates in a private health insured South African population
Solanki G, Fawcus S, Daviaud E.
HIV-1 drug resistance surveillance among parturient women on anti-retroviral therapy in the Eastern Cape, South Africa: implications for elimination of mother-to-child transmission.
Adeniyi OV, Obi CL, Goon DT, Iweriebor B, Ajayi AI, Lambert J, Okoh A.
Workplace violence in Bangladesh's garment industry
Gibbs A, Jewkes R, Willan S, Al Mamun M, Parvin K, Yu M, Naved R.
Occurrence and risk evaluation of organochlorine contaminants in surface water along the course of Swartkops and Sundays River Estuaries, Eastern Cape Province, South Africa
Olisah C, Adeniji AO, Okoh OO, Okoh AI.
Response by Naidoo et al to letter regarding article "Early life factors and longitudinal blood pressure trajectories are associated with elevated blood pressure in early adulthood: BT20 Cohort"
Naidoo S, Kagura J, Fabian J, Norris SA.
More research is needed on digital technologies in violence against women
Jewkes R, Dartnall E.
Point of care Xpert MTB/RIF versus smear microscopy for tuberculosis diagnosis in southern African primary care clinics: a multicentre economic evaluation
Pooran A, Theron G, Zijenah L, Chanda D, Clowes P, Mwenge L, Mutenherwa F, Lecesse P, Metcalfe J, Sohn H, Hoelscher M, Pym A, Peter J, Dowdy D, Dheda K.
Low birthweight: will new estimates accelerate progress?
Doherty T, Kinney M.
Gender equality and health: laying the foundations for change
George AS, Amin A, GarcIa-Moreno C, Sen G.
Decriminalisation of recreational cannabis in South Africa
Parry C, Myers B, Caulkins J.
The emerging role of myeloid-derived suppressor cells in tuberculosis.
Magcwebeba T, Dorhoi A, du Plessis N.
Synthesis and structure-activity relationship of 1-(5-isoquinolinesulfonyl)piperazine analogues as inhibitors of Mycobacterium tuberculosis IMPDH
Singh V, Pacitto A, Donini S, Ferraris DM, Boros S, Illyes E, Szokol B, Rizzi M, Blundell TL, Ascher DB, Pato J, Mizrahi V.
Longitudinal changes in spirometry in perinatally HIV-infected South African adolescents on antiretroviral therapy
Githinji LN, Gray DM, Hlengwa S, Machemedze T, Zar HJ.
Understanding the full clinical spectrum of childhood diarrhoea in low-income and middle-income countries.
Groome MJ, Parashar UD.
The duopoly of ten-valent and 13-valent pneumococcal conjugate vaccines: do they differ?
Madhi SA, Goldblatt D.Madhi SA, Goldblatt D.
SAMRC research on Femicide and Child homicide
Prof. Naeemah Abrahams & Bianca Dekel
Lower respiratory tract infections in children in a well-vaccinated South African birth cohort: spectrum of disease and risk factors
le Roux DM, Nicol MP, Myer L, Vanker A, Stadler JAM, von Delft E, Zar HJ.
Antiretroviral switching and bedaquiline treatment of drug-resistant tuberculosis HIV co-infection
O'Donnell MR, Padayatchi N, Daftary A, Orrell C, Dooley KE, Rivet Amico K, Friedland G.
The microbiome and tuberculosis: state of the art, potential applications, and defining the clinical research agenda
Naidoo CC, Nyawo GR, Wu BG, Walzl G, Warren RM, Segal LN, Theron G.
How are countries in sub-Saharan African monitoring the impact of programmes to prevent vertical transmission of HIV?
Goga A, Singh Y, Jackson D, Mukungunugwa S, Wafula R, Eliya M, Ng'ambi WF, Nabitaka L, Chirinda W, Bhardwaj S, Essajee S, Hayashi C, Pillay Y.
The STREAM trial: missed opportunities and lessons for future clinical trials
Loveday M, Reuter A, Furin J, Seddon JA, Cox H.
Factors that influence parents' and informal caregivers' acceptance of routine childhood vaccination: a qualitative evidence synthesis
Cooper S, Schmidt BM, Sambala EZ, Swartz A, Colvin CJ, Leon N, Betsch C, Wiysonge CS.
A moxifloxacinbased regimen for the treatment of recurrent drug-sensitive pulmonary tuberculosis: an open-label randomised controlled trial.
Perumal R, Padayatchi N, Yende-Zuma N, Naidoo A, Govender D, Naidoo K.
Improving breastfeeding practices at scale
Rollins N, Doherty T.
Expanding the anti-TB arsenal
Mizrahi V, Warner DF.
Engaging men to support women in science, medicine, and global health
Ratele K, Verma R, Cruz S, Khan AR.
The African Prospective study on the Early Detection and Identification of Cardiovascular disease and Hypertension (African-PREDICT): design, recruitment and initial examination
Schutte AE, Gona PN, Delles C, Uys AS, Burger A, Mels CM, Kruger R, Smith W, Fourie CM, Botha S, Lammertyn L, van Rooyen JM, Gafane-Matemane LF, Mokwatsi GG, Breet Y, Kruger HS, Zyl TV, Pieters M, Zandberg L, Louw R, Moss SJ, Khumalo IP, Huisman HW.
Interaction of herbal products with prescribed medications: a systematic review and meta-analysis
Awortwe C, Bruckmueller H, Cascorbi I.
Prevalence of congenital cytomegalovirus infection and associated risk of in-utero HIV acquisition in a high HIV prevalence setting, South Africa
Pathirana J, Groome M, Dorfman J, Kwatra G, Boppana S, Cutland C, Jones S, Madhi SA.
Hope for patients with X-linked hypophosphataemia?
Pettifor JM.
Integrating mental health with other non-communicable diseases
Stein DJ, Benjet C, Gureje O, Lund C, Scott KM, Poznyak V, van Ommeren M
Inflammation and oxidative stress in an obese state and the protective effects of gallic acid
Dludla PV, Nkambule BB, Jack B, Mkandla Z, Mutize T, Silvestri S, Orlando P, Tiano L, Louw J, Mazibuko-Mbeje SE.
Early Life factors and longitudinal blood pressure trajectories are associated with elevated blood pressure in early adulthood
Naidoo S, Kagura J, Fabian J, Norris SA.
Batf2 differentially regulates tissue immunopathology in Type 1 and Type 2 diseases
Guler R, Mpotje T, Ozturk M, Nono JK, Parihar SP, Chia JE, Abdel Aziz N, Hlaka L, Kumar S, Roy S, Penn-Nicholson A, Hanekom WA, Zak DE, Scriba TJ, Suzuki H, Brombacher F.
Conservation of white rhinoceroses threatened by bovine tuberculosis, South Africa, 2016-2017
Miller MA, Buss P, Parsons SDC, Roos E, Chileshe J, Goosen WJ, van Schalkwyk L, de Klerk-Lorist LM, Hofmeyr M, Hausler G, Rossouw L, Manamela T, Mitchell EP, Warren R, van Helden P.
Urgency for South Africa to prioritise cardiovascular disease management
Schutte AE.
Host regulators of liver fibrosis during human schistosomiasis
Kamdem SD, Moyou-Somo R, Brombacher F, Nono JK.
Neutrophils: Innate effectors of tb resistance?
Kroon EE, Coussens AK, Kinnear C, Orlova M, Moller M, Seeger A, Wilkinson RJ, Hoal EG, Schurr E.
Screening strategies for hypertension
Schmidt BM, Durao S, Toews I, Bavuma CM, Meerpohl JJ, Kredo T.
Measles immunity at 4.5 years of age following vaccination at 9 and 15-18 months of age among HIV-infected, HIV-exposed-uninfected and HIV-unexposed children
Mutsaerts E, Nunes MC, van Rijswijk MN, Klipstein-Grobusch K, Otwombe K, Cotton MF, Violari A, Madhi SA.
Birth HIV testing and paediatric treatment programmes
Goga A.
Intra-breath measures of respiratory mechanics in healthy African infants detect risk of respiratory illness in early life
Gray DM, Czovek D, McMillan L, Turkovic L, Stadler JAM, Vanker A, Radics BL, Gingl Z, Hall GL, Sly PD, Zar HJ, Hantos Z.
Silver nanoparticles mediated by Callistemon citrinus extracts and their antimalaria, antitrypanosoma and antibacterial efficacy
Larayetan R, Ojemaye MO, Okoh OO, Okoh AI.
Protective effect of triterpenes against diabetes-induced beta-cell damage: an overview of in vitro and in vivo studies
Mabhida SE, Dludla PV, Johnson R, Ndlovu M, Louw J, Opoku AR, Mosa RA.
Village community mobilization is associated with reduced HIV incidence in young South African women participating in the HPTN 068 study cohort
Lippman SA, Leddy AM, Neilands TB, Ahern J, MacPhail C, Wagner RG, Peacock D, Twine R, Goin DE, Gomez-Olive FX, Selin A, Tollman SM, Kahn K, Pettifor A.
Schistosomiasis burden and its association with lower measles vaccine responses in school children from rural Cameroon
Nono JK, Kamdem SD, Netongo PM, Dabee S, Schomaker M, Oumarou A, Brombacher F, Moyou-Somo R.
The Foxp3+ regulatory T-cell population requires IL-4Ralpha signaling to control inflammation during helminth infections.
Abdel Aziz N, Nono JK, Mpotje T, Brombacher F.
Uncoupling proteins as a therapeutic target to protect the diabetic heart
Dludla PV, Nkambule BB, Tiano L, Louw J, Jastroch M, Mazibuko-Mbeje SE
Genetic resistance to mycobacterium tuberculosis infection and disease
Möller M, Kinnear CJ, Orlova M, Kroon EE, van Helden PD, Schurr E, Hoal EG
Death of Mycobacterium tuberculosis by l-arginine starvation
Mizrahi V, Warner DF
Treatment of bronchiectasis exacerbations in children: which antibiotic?
Zar HJ, Nicol MP
The coming of age of drug-susceptibility testing for tuberculosis
Cox H, Mizrahi V
Genetic risk score for adult body mass index associations with childhood and adolescent weight gain in an African population
Munthali RJ, Sahibdeen V, Kagura J, Hendry LM, Norris SA, Ong KK, Day FR, Lombard Z
Metacarpal indices and their association with fracture in South African children and adolescents
Magan A, Micklesfield LK, Norris SA, Thandrayen K, Munthali RJ, Pettifor JM
Lanosteryl triterpenes from Protorhus longifolia as a cardioprotective agent: a mini review.
Sangweni NF, Dludla PV, Mosa RA, Kappo AP, Opoku A, Muller CJF, Johnson R
Determination of levels of some metal contaminants in the freshwater environments of Osun State, Southwest Nigeria: a risk assessment approach to predict health threat
Titilawo Y, Adeniji A, Adeniyi M, Okoh A
Concentrations of arsenic and lead in residential garden soil from four Johannesburg neighborhoods
Mathee A, Kootbodien T, Kapwata T, Naicker N
Tracking trends in HIV/AIDS mortality pre-and-post ART: South Africa 1997 to 2012
Pillay-van Wyk V, Bradshaw D, Msemburi W, Dorrington R, Laubscher R, Groenewald P
Community mobilization to modify harmful gender norms and reduce HIV risk: results from a community cluster randomized trial in South Africa
Pettifor A, Lippman SA, Gottert A, Suchindran CM, Selin A, Peacock D, Maman S, Rebombo D, Twine R, Gomez-Olive FX, Tollman S, Kahn K, MacPhail C
The potential use of rifabutin for treatment of patients diagnosed with rifampicin-resistant tuberculosis
Whitfield MG, Warren RM, Mathys V, Scott L, de Vos E, Stevens W, Streicher EM, Groenen G, Sirgel FA, van Rie A
Susceptibility to tuberculosis is associated with PI3K-dependent increased mobilization of neutrophils
Leisching GR
Role of district health management teams in child health strategies
Doherty T, Tran N, Sanders D, Dalglish SL, Hipgrave D, Rasanathan K, Sundararaman T, Ved R, Mason E
Drug permeation and metabolism in Mycobacterium tuberculosis: Prioritising local exposure as essential criterion in new TB drug development.
Tanner L, Denti P, Wiesner L, Warner DF.
Bicomponent fibres for controlled release of volatile mosquito repellents.
Sibanda M, Focke W, Braack L, Leuteritz A, Brünig H, Tran NHA, Wieczorek F, Trümper W.
Targeted pregnancy and HIV prevention risk-reduction counselling for young women: Lessons learned from biomedical prevention trials
Ramjee G, Dassaye R, Reddy T, Wand H.
Describing the diurnal relationships between objectively measured mother and infant physical activity.
Prioreschi A, Brage S, Westgate K, Micklesfield LK.
Drug-resistant tuberculosis: challenges and opportunities for diagnosis and treatment.
Koch A, Cox H, Mizrahi V.
Autosomal dominant IFN-γR1 deficiency presenting with both atypical mycobacteriosis and tuberculosis in a BCG-vaccinated South African patient.
Glanzmann B, Moller M, Moncada-Velez M, Peter J, Urban M, van Helden PD, Hoal EG, de Villiers N, Glashoff RH, Nortje R, Bustamante J, Abel L, Casanova JL, Boisson-Dupuis S, Esser M, Kinnear CJ.
What are the financial implications of the 2017 AHA/ACC high blood pressure guideline?
Schutte AE.
Factors Influencing the umbilical cord blood stem cell industry: An evolving treatment landscape.
Dessels C, Alessandrini M, Pepper MS.
Iron loading, alcohol and mortality: A prospective study.
Schutte R, Huisman H, Mels CMC, Botha S, Kruger R, Smith W, Kruger IM, Hawkins M, Smith L, Breet Y, Schutte AE.
Challenges of cardiovascular disease risk evaluation in people living with HIV infection.
Kengne AP, Ntsekhe M.
Prevalence and risk factors for child mental disorders in a population-based cohort of HIV-exposed and unexposed African children aged 7-11 years.
Rochat TJ, Houle B, Stein A, Pearson RM, Bland RM.
Risk of nephrotoxicity in patients with drug-resistant tuberculosis treated with Kanamycin/Capreomycin with or without concomitant use of tenofovir-containing antiretroviral therapy.
Perumal R, Abdelghani N, Naidu N, Yende-Zuma N, Dawood H, Naidoo K, Singh N, Padayatchi N.
C-type lectin receptors in asthma.
Hadebe S, Brombacher F, Brown GD.
Tobacco cessation in low- and middle-income countries: Some challenges and opportunities.
Peer N, Kengne AP.
Contracting out to improve the use of clinical health services and health outcomes in Low- and Middle-Income Countries.
Odendaal WA, Ward K, Uneke J, Uro-Chukwu H, Chitama D, Balakrishna Y, Kredo T.
The Effects of School-Based Condom Availability Programs (CAPs) on Condom Acquisition, Use and Sexual Behavior: A Systematic Review
Timothy Wang, Mark Lurie, Darshini Govindasamy, Catherine Mathews
From symptom discovery to treatment - women's pathways to breast cancer care: A cross-sectional study
Moodley J, Cairncross L, Naiker T, Constant D
Seroprevalence of mycobacterium bovis infection in warthogs (phacochoerus africanus) in bovine tuberculosis-endemic regions of South Africa
Roos EO, Olea-Popelka F, Buss P, de Klerk-Lorist LM, Cooper D, van Helden PD, Parsons SDC, Miller MA
The prevalence of gestational diabetes mellitus amongst black South African women is a public health concern
Macaulay S, Ngobeni M, Dunger DB, Norris SA.
Fate and impact of phthalates in activated sludge treated municipal wastewater on the water bodies in the Eastern Cape, South Africa
Salaudeen T, Okoh O, Agunbiade F, Okoh A
Mycobacterium tuberculosis
Koch A, Mizrahi V
OAS1, 2 and 3: Significance during active TB?
Leisching G, Wiid I, Baker B
Priming the tuberculosis drug pipeline: New antimycobacterial targets and agents
Evans JC, Mizrahi V
Mitigating the effect of persistent postnatal depression on child outcomes through an intervention to treat depression and improve parenting: A randomised controlled trial
Stein A, Netsi E, Lawrence PJ, Granger C, Kempton C, Craske MG, Nickless A, Mollison J, Stewart DA, Rapa E, West V, Scerif G, Cooper PJ, Murray L
Developmental origins of health and disease in Africa-influencing early life
Davies JI, Macnab AJ, Byass P, Norris SA, Nyirenda M, Singhal A, Sobngwi E, Daar AS.
Modifiable stroke risk factors in Africa: Lessons from siren
Kengne AP, Mayosi BM.
Genetic diversity and potential routes of transmission of mycobacterium bovis in Mozambique
Machado A, Rito T, Ghebremichael S, Muhate N, Maxhuza G, Macuamule C, Moiane I, Macucule B, Marranangumbe AS, Baptista J, Manguele J, Koivula T, Streicher EM, Warren RM, Kallenius G, van Helden P, Correia-Neves M.
House dust mite induced allergic airway disease is attenuated in CD11c(CRE)IL-4Ralpha(-/L) degrees (X) mice
Nieuwenhuizen NE, Kirstein F, Hoving JC, Brombacher F
Alterations in male reproductive hormones in relation to environmental DDT exposure
Bornman M, Delport R, Farías P, Aneck-Hahn N, Patrick S, Millar RP, de Jager C.
Cohort PROFILE: Health and ageing in Africa: A longitudinal study of an INDEPTH community in South Africa
Gomez-Olive FX, Montana L, Wagner RG, Kabudula CW, Rohr JK, Kahn K, Barnighausen T, Collinson M, Canning D, Gaziano T, Salomon JA, Payne CF, Wade A, Tollman SM, Berkman L.
Renewing the focus on health care for sexually assaulted children and adolescents
Jewkes R.
Support for alcohol policies among drinkers in Mongolia, New Zealand, Peru, South Africa, St Kitts and Nevis, Thailand and Vietnam: Data from the international alcohol control study
Parry CDH, Londani M, Enkhtuya P, Huckle T, Piazza M, Gray-Phillip G, Chaiyasong S, Viet Cuong P, Casswell S
Rotavirus strain diversity in eastern and southern African countries before and after vaccine introduction
Seheri LM, Magagula NB, Peenze I, Rakau K, Ndadza A, Mwenda JM, Weldegebriel G, Steele AD, Mphahlele MJ
Describing objectively measured physical activity levels, patterns, and correlates in a cross sectional sample of infants and toddlers from South Africa
Prioreschi A, Brage S, Hesketh KD, Hnatiuk J, Westgate K, Micklesfield LK
APP-supported promotion of child growth and development by community health workers in Kenya: Feasibility and acceptability study
van Heerden A, Sen D, Desmond C, Louw J, Richter L
Burden of respiratory syncytial virus infection in South African HIV-infected and HIV-uninfected pregnant and post-partum women: A longitudinal cohort study
Madhi SA, Cutland CL, Downs S, Jones S, van Niekerk N, Simoes EAF, Nunes MC
Exchange transfusions for extreme hypertriglyceridemia in a 7-week-old infant with multi-organ failure
Ghoor S, Berlyn P, Brey N
A systematic review of the efficacy and safety of intrapericardial fibrinolysis in patients with pericardial effusion
Wiyeh AB, Ochodo EA, Wiysonge CS, Kakia A, Awotedu AA, Ristic A, Mayosi BM
Exome sequencing identifies a novel MAP3K14 mutation in recessive atypical combined immunodeficiency
Schlechter N, Glanzmann B, Hoal EG, Schoeman M, Petersen BS, Franke A, Lau YL, Urban M, van Helden PD, Esser MM, Moller M, Kinnear C
Interleukin-4 Receptor Alpha: From innate to adaptive immunity in murine models of cutaneous leishmaniasis
Hurdayal R, Brombacher F
Neuroimaging genomics in psychiatry-a translational approach. Genome Medicine
Mufford MS, Stein DJ, Dalvie S, Groenewold NA, Thompson PM, Jahanshad N.
Reduction of in utero lead exposures in South African populations: Positive impact of unleaded petrol
Rollin HB, Olutola B, Channa K, Odland JO
Spatial distribution of extensively drug-resistant tuberculosis (XDR TB) patients in KwaZulu-Natal, South Africa
Kapwata T, Morris N, Campbell A, Mthiyane T, Mpangase P, Nelson KN, Allana S, Brust JCM, Moodley P, Mlisana K, Gandhi NR, Shah NS
Point-of-care chest ultrasound in South African children with suspected pulmonary tuberculosis
Heuvelings CC, Belard S, Andronikou S, Jamieson-Luff N, Grobusch M, Zar H.
Innovation at the intersection of alcohol and HIV research
van Heerden A, Tomlinson M, Skeen S, Parry C, Bryant K, Rotheram-Borus MJ.
High prevalence of HIV and Non-Communicable Disease (NCD) risk factors in rural KwaZulu-Natal, South Africa
van Heerden A, Barnabas RV, Norris SA, Micklesfield LK, van Rooyen H, Celum C.
Is 24-hour central blood pressure superior to 24-hour brachial blood pressure for predicting organ damage?
Schutte AE, Laurent S.
Financial arrangements for health systems in low-income countries: An overview of systematic reviews
Wiysonge CS, Paulsen E, Lewin S, Ciapponi A, Herrera CA, Opiyo N, Pantoja T, Rada G, Oxman AD
The association between elevated blood lead levels and violent behavior during late adolescence: The South African Birth to Twenty Plus cohort
Nkomo P, Mathee A, Naicker N, Galpin J, Richter LM, Norris SA
Women's and men's reports of past-year prevalence of intimate partner violence and rape and women's risk factors for intimate partner violence: A multicountry cross-sectional study in Asia and the Pacific
Jewkes R, Fulu E, Tabassam Naved R, Chirwa E, Dunkle K, Haardorfer R, Garcia-Moreno C
IL-4-producing B cells regulate T helper cell dichotomy in type 1- and type 2-controlled diseases
Hurdayal R, Ndlovu HH, Revaz-Breton M, Parihar SP, Nono JK, Govender M, Brombacher F
Nine-valent human papillomavirus vaccine: Great science, but will it save lives?
Denny L
Protein Kinase C-Delta (PKCDELTA), a marker of inflammation and tuberculosis disease progression in humans, is important for optimal macrophage killing effector functions and survival in mice
Parihar SP, Ozturk M, Marakalala MJ, Loots DT, Hurdayal R, Beukes D, Van Reenen M, Zak DE, Mbandi SK, Darboe F, Penn-Nicholson A, Hanekom WA, Leitges M, Scriba TJ, Guler R, Brombacher F.
Cohort profile: The Siyakhula Cohort, rural South Africa
Rochat TJ, Houle B, Stein A, Pearson RM, Newell ML, Bland RM
The Amagugu intervention for disclosure of maternal HIV to uninfected primary school-aged children in South Africa: A randomised controlled trial
Rochat TJ, Stein A, Cortina-Borja M, Tanser F, Bland RM
Socioeconomic differences in mortality in the antiretroviral therapy era in Agincourt, rural South Africa, 2001-13: A population surveillance analysis
Kabudula CW, Houle B, Collinson MA, Kahn K, Gomez-Olive FX, Tollman S, Clark SJ
Mortality and socioeconomic status: The vicious cycle between poverty and ill health.
Pillay-van Wyk V, Bradshaw D
Comparison of traditional culture and molecular QPCR for detection of simultaneous carriage of multiple pneumococcal serotypes in African children
Olwagen CP, Adrian PV, Madhi SA
Susceptibility of mycobacterium tuberculosis cytochrome bd oxidase mutants to compounds targeting the terminal respiratory oxidase, cytochrome c
Moosa A, Lamprecht DA, Arora K, Barry CE 3rd, Boshoff HIM, Ioerger TR, Steyn AJC, Mizrahi V, Warner DF.
Cochrane corner: Beta-blockers for hypertension
Wiysonge CS, Bradley HA, Volmink J, Mayosi BM.
The cross-national epidemiology of social anxiety disorder: Data from the world mental health survey initiative
Stein DJ, Lim CCW, Roest AM, de Jonge P, Aguilar-Gaxiola S, Al-Hamzawi A, Alonso J, Benjet C, Bromet EJ, Bruffaerts R, de Girolamo G, Florescu S, Gureje O, Haro JM, Harris MG, He Y, Hinkov H, Horiguchi I, Hu C, Karam A, Karam EG, Lee S, Lepine JP, Navarro-Mateu F, Pennell BE, Piazza M, Posada-Villa J, Ten Have M, Torres Y, Viana MC, Wojtyniak B, Xavier M, Kessler RC, Scott KM
Advances in the diagnosis of pneumonia in children
Zar HJ, Andronikou S, Nicol MP
Living arrangements, disability and gender of older adults among rural South Africa
Schatz E, Ralston M, Madhavan S, Collinson MA, Gomez-Olive FX
Sugary beverage taxation in South Africa: Household expenditure, demand system elasticities, and policy implications
Stacey N, Tugendhaft A, Hofman K.
Interleukin-4 receptor alpha is still required after Th2 polarization for the maintenance and the recall of protective immunity to Nematode infection
Nono JK, Ndlovu H, Abdel Aziz N, Mpotje T, Hlaka L, Brombacher F.
The protective role of oestradiol against silent myocardial ischemia and hypertension risk in South African men: The SABPA study
Malan NT, von Känel R, Steyn HS, Kruger R, Malan L.
Changes in host immune-endocrine relationships during tuberculosis treatment in patients with cured and failed treatment outcomes
Kleynhans L, Ruzive S, Ehlers L, Thiart L, Chegou NN, Conradie M, Kriel M, Stanley K, van der Spuy GD, Kidd M, van Helden PD, Walzl G, Ronacher K.
Efficacy of maternal influenza vaccination against all-cause lower respiratory tract infection hospitalizations in young infants: Results from a randomized controlled trial
Nunes MC, Cutland CL, Jones S, Downs S, Weinberg A, Ortiz JR, Neuzil KM, Simoes EAF, Klugman KP, Madhi SA
The incremental value of repeated induced sputum and gastric aspirate samples for the diagnosis of pulmonary tuberculosis in young children with acute community-acquired pneumonia
Moore DP, Higdon MM, Hammitt LL, Prosperi C, DeLuca AN, Da Silva P, Baillie VL, Adrian PV, Mudau A, Deloria Knoll M, Feikin DR, Murdoch DR, O'Brien KL, Madhi SA.
Diagnosis of pulmonary tuberculosis in HIV-infected and uninfected children using Xpert MTB/RIF ultra
Zar HJ, Workman L, Nicol MP.
Safety and immunogenicity of a parenteral P2-VP8-P[8] subunit rotavirus vaccine in toddlers and infants in South Africa: A randomised, double-blind, placebocontrolled trial
Groome MJ, Koen A, Fix A, Page N, Jose L, Madhi SA, McNeal M, Dally L, Cho I, Power M, Flores J, Cryz S.
Psychiatric practice: Caring for patients, collaborating with partners, or marketing to consumers?
Stein DJ.
Assessing the complexity of interventions within systematic reviews: Development, content and use of a new tool (iCAT-SR). BMC Medical Research Methodology
Lewin S, Hendry M, Chandler J, Oxman AD, Michie S, Shepperd S, Reeves BC, Tugwell P, Hannes K, Rehfuess EA, Welch V, McKenzie JE, Burford B, Petkovic J, Anderson LM, Harris J, Noyes J.
Age-dependent development of left ventricular wall thickness in type 2 diabetic (db/db) mice is associated with elevated low-density lipoprotein and triglyceride serum levels
Dludla PV, Essop MF, Gabuza KB, Muller CJ, Louw J, Johnson R.
Targeting the aryl hydrocarbon receptor nuclear translocator complex with DMOG and Stemregenin 1 improves primitive hematopoietic stem cell expansion
Jackson CS, Durandt C, Janse van Rensburg I, Praloran V, Brunet de la Grange P, Pepper MS.
Immunization with 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugate vaccine (PHiD-CV) according to different schedules in infants in South Africa: A phase III trial
Madhi SA, Koen A, Jose L, Moreira M, van Niekerk N, Cutland C, François N, Ruiz-Guiñazú J, Yarzabal JP, Borys D, Schuerman L.
Sustained inhibition of HBV replication in vivo after systemic injection of AAVs encoding artificial antiviral primary microRNAs
Maepa MB, Ely A, Grayson W, Arbuthnot P.
Impact of CYP2D6 genotype on amitriptyline efficacy for the treatment of diabetic peripheral neuropathy: A pilot study
Chaudhry M, Alessandrini M, Rademan J, Dodgen TM, Steffens FE, van Zyl DG, Gaedigk A, Pepper MS
Recent advances in understanding hypertension development in sub-Saharan Africa
Schutte AE, Botha S, Fourie CM, Gafane-Matemane LF, Kruger R, Lammertyn L, Malan L, Mels CM, Schutte R, Smith W, van Rooyen JM, Ware LJ, Huisman HW.
Psychosocial group interventions to improve psychological well-being in adults living with HIV
van der Heijden I, Abrahams N, Sinclair D.
Efficacy and safety of agomelatine (10 or 25 mg/day) in non-depressed out-patients with generalized anxiety disorder: A 12-week, double-blind, placebo-controlled study
Stein DJ, Ahokas A, Jarema M, Avedisova AS, Vavrusova L, Chaban O, Gruget C, Olivier V, Picarel-Blanchot F, de Bodinat C.
Cookstove options for safety and health: Comparative analysis of technological and usability attributes
Kimemia D, Van Niekerk A.