Page 10 - Annual Report - Summative Report 2024-2025

pharmacogenomics portfolio was evaluated by an programme. The programme focuses on creating a
expert panel to assess progress, determine the next unified ecosystem, garnering the participation of all
steps for each project and identify opportunities for national role players to implement a pilot phase and
further product development. set up a national centralized data repository.

• Two projects subsequently received follow on funding • An assessment of infrastructure and technology
for product development of pharmacogenomics needs, including cyber infrastructure solutions for
solutions in hypertension and breast cancer secure data storage and analysis was completed.
diagnostics. An important highlight was progression The programme will use shared best practices and
of planning for the South African 110K Human collaboration models for efficient genomic research
Genome Programme (SA110K HGP). A workshop workflows to adapt and standardize sequencing
in 2024 brought together key stakeholders from workflows across decentralized laboratory
research institutions, government agencies, and operations.
industry partners to discuss how to advance genomic
research and precision medicine in South Africa. The • Partnerships are being established with industry
first engagements of the consortium commenced leaders such as Illumina, MGI, and Oxford Nanopore
from May 2024 and a proposal was submitted and to foster knowledge exchange, technology transfer,
approved in September 2024 for funding towards and capacity building.
the pilot (10k) phase of the SA Human Genome

GRANTS INNOVATION

STRATEGIC SAMRC STRATEGIC
PROJECTS & GRANT FUNDING SHIP
PROGRAMMES PROGRAMMES PARTNERSHIPS

Technology Global Health
Sisonke and Project SAAVI HeLTI SHIP JPIAMR Transfer Innovation SAMRC-TIA
SHERPA GRADIENT Programs Seed Fund
Office Accelerator

Self-initiated ERA-
VaxCo mRNA TT Research ANRS TB PerMed E Cape
Study Hub Cap Dev
Grants JTC 2022

Grand Grand
Biovac Strategic Newton
OVC Stuly IKS Grants Fund AMR Challenges Challenges
AMR Infodemics

MRC UKRI Grand
CSSFF- EU-Africa COVID-19 NCD, One Grand Challenges
SAMRC Challenges
Cap Dev PerMed Grants Health, Multi- AI Climate &
morbidities Health

Funders’ NIH/
KIW Mpox
Forum HIV/TB

Brian
10k Pilot
Genomics

Overview of the grant and innovation programmes and strategic projects managed by the Grants
Innovation and Product Development unit.

10 SAMRC SUMMATIVE REPOR T 2024-25