Page 136 - SAMRC AnnualReport 2025-26

Artificial Intelligence in Medical innovative work was published in the esteemed
and Health Research journal Nature Communications in 2023.

Artificial intelligence has become a vital part of The Unit has also applied AI to precision medicine
the Unit’s research strategy, especially in speeding approaches to tailor drug dosages for African
up drug discovery and optimising drug dosing. populations. This research investigates how
The Unit has utilised in-house datasets to create genetic diversity contributes to variability in drug
AI-driven models that support essential decision- exposure, efficacy, and safety for medicines used
making in medicines discovery. Early results have to treat malaria and TB. The findings have shown
shown that AI can boost operational efficiency by at how AI can optimise dosing regimens for African
least 40%, while greatly lowering the costs linked to patients, supporting safer, more effective treatment
drug discovery in Africa, representing a significant strategies. This work was also published in Nature
advancement for resource-limited settings. This Communications in 2025.

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