Page 11 - SAMRC AnnualReport 2025-26
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G EN ER A L I N F O R M A T I O N




            ACHIEVEMENTS AND HIGHLIGHTS





            Responding to the withdrawal                       once-off grants for postgraduate students (MSc and

            of US funding from the National                    PhD) whose studies were directly affected, alongside
            Health Research and Innovation                     providing Equipment and Maintenance Support to
                                                               ensure that essential research equipment remained
            Enterprise in South Africa                         functional.

            Internal Response                                   Through these interventions, the SAMRC contributed
            In 2025, the South African Medical Research Council   as a stabilising force during this difficult period as
            (SAMRC) faced significant pressure on HIV and TB   well as aided to preserve research momentum and
            research following reductions in United States (US)   ensured the continuity of high-quality health research
            federal funding, which had traditionally supported   within the SAMRC Intramural and Extramural research
            a  substantial  portion  of  the  country’s  HIV  and  TB   environment. The experience also accelerated a
            research  portfolio.  In  response  to  the  significant   shift toward greater sustainability, integration, and
            disruption of the South African research landscape   national alignment of health research, which may,
            caused by the withdrawal of US federal funding, the   in the end, see 2025 as the year of a shift to more
            SAMRC  through  various  mechanisms,  proactively   resilient, flexible, and independent research in Africa.
            intervened to protect the nation's scientific progress
            by cushioning the impact of these sudden financial   External Response
            losses.                                            The SAMRC, through the office of the President and
                                                               the  Grants,  Innovation  and  Product  Development
            Within the intramural research programme, to
            mitigate disruption and protect critical programmes,   (GIPD)  unit,  also  mounted  a  broader,  nationwide
            the SAMRC adopted a combination of stabilisation   response to the funding crisis by establishing
            measures, strategic reprioritisation, and system   the National Health Research Enterprise (NHRE)
            integration. Hardest hit were programmes focused   Programme. The SAMRC President, with support
            on HIV, TB and diversity-focused research; however,   from  the  National  Department  of  Health,
            these rapidly pivoted to other research areas such as   spearheaded  efforts  to  raise  funding  to  support
            Mpox or cholera, considered new and diverse funding   affected institutions and organisations, ensuring a
            streams and consolidated staff and infrastructure.   strategic, locally driven response to safeguard South
            Our BRILLIANT programme of HIV vaccine research,   Africa’s national health research enterprise from
            terminated by USAID very early in January 2025, has   severe attrition.
            continued, albeit in a more condensed programme,   In April 2025, a formal proposal titled “Proposal for
            with new committed funders. As a first and immediate   Support of South African National Health Research
            response, the ELMA Relief Foundation committed     Enterprise in Response to U.S. Funding Withdrawal”
            R3  million  to  support  the  BRILLIANT  pre-clinical   was submitted to the National Department of
            HIV  programme,  thereby  ensuring  the  continuity   Health, National Treasury and Department of
            of  this  component.  Staff  who  were  appointed  on   Science, Technology and Innovation (DSTI) urgently
            terminated programmes were consulted at every      requesting a commitment from government to
            new  development  to  mitigate  workforce  losses  as
            much as possible and ensure that critical expertise   the value of R400 million with the promise of co-
            was retained within the organisation.              funding support from the Gates Foundation and the
                                                               Wellcome Trust. In June 2025, a letter of response
            As one way to support research during these uncertain   was received from the Finance Minister, Mr. Enoch
            times,  the  SAMRC  reaffirmed  its  commitment    Godongwana, addressed to the Minister of Health,
            to strengthening South Africa’s research system    Dr Aaron Motsoaledi, outlining support to allocate
            by providing targeted support to the Extramural    a total of R400 million over 3 years to the SAMRC,
            Research Units (EMUs). This strategic intervention   with  R132  million  of  this  allocation  for  immediate
            provided  critical  interim  financial  support  through   release under the Section 16 Emergency Allocation.





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