Page 145 - SAMRC AnnualReport 2025-26
P. 145

P E R FOR M A NC E  I N FOR M A T I ON






                                                               Primate Unit and
                                                               Delft Animal Centre





                                                               UNIT DIRECTOR:
                                                               Dr. Chesa Chauke
                                                               chesa.chauke@mrc.ac.za







            Overview of the Research Unit                      Key Milestones and Achievements

            The Primate Unit and Delft Animal Centre (PUDAC)   During the 2025/2026 fiscal year, PUDAC focused on
            is a research facility registered with the South   strengthening its research capacity, infrastructure,
            African  Veterinary  Council (SAVC), dedicated to   and strategic collaborations to advance biomedical
            promoting health through high-quality, ethical     sciences and support impactful health research.
            preclinical research. Operating in accordance      A  primary  goal was  upgrading  research  facilities
            with national regulations and standards, including   to meet regulatory standards and enhance
            SANS 10386: 2021, the facility maintains the highest   experimental capabilities. Notable initiatives
            standards of animal welfare and scientific integrity   included completing Animal BSL-2 renovations for
            in all its activities.                             Species 1, beginning the second phase of ABSL-2
                                                               for Species 2, and expanding the rodent research
            PUDAC  supports  the  development  of new  drugs   facility with auxiliary spaces and a second HVAC
            and vaccines targeting major global health         system to ensure optimal environmental conditions.
            challenges, including HIV/AIDS, infectious diseases,   Additionally, outdoor enclosures for vervet monkeys
            and non-communicable diseases (NCDs). Through      were constructed to promote natural behaviours
            partnerships with local and international research
            institutions, the centre contributes to innovations
            with the potential to improve public health outcomes
            both in South Africa and worldwide. Ongoing
            investment in infrastructure and service delivery
            further underpins its long-term sustainability and
            competitiveness.
            The facility contains specialised animal resources,
            including  captive-bred  rhesus  macaques  for  HIV/
            AIDS  vaccine  research  and  vervet  monkeys  for
            metabolic and non-communicable disease studies.
            PUDAC also supports research with additional
            resources, such as a horse herd for blood products
            and access to rodent models for early-stage
            research and training initiatives.
            Through ongoing infrastructure upgrades and
            the expansion of research capabilities, PUDAC
            continues to strengthen its role as a key platform
            for translational science. Current initiatives include
            advancing  HIV  research  models  and  developing
            diet-induced disease models, thereby broadening        PUDAC staff members receiving training on
                                                                   laboratory safety and compliance workshop.
            opportunities for collaboration and impact across
            the biomedical research landscape.



                                                           SA M R C  A N N U A L R EP O R T 2 0 2 5 / 2 0 2 6  143
   140   141   142   143   144   145   146   147   148   149   150