Page 162 - SAMRC AnnualReport 2025-26

standardised digital diagnostics that can be contributions to a peer-reviewed publication on AI-
deployed within the public health sector to address powered advances in Type II endometrial cancer, as
human resource and infrastructure constraints in well as AI-focused chapters in major international
South Africa's pathology services. volumes on precision oncology.

In the field of multi-omics and precision oncology, At the collaborative level, PORU's participation in
PORU uses data-driven platforms that integrate the GA4GH Study Group on Human Exposome
genomics, transcriptomics, spatial biology, and Data Standards ensures that African cohorts are
systems oncology to identify RNA splicing signatures, represented in emerging global precision health
tumour mutational profiles, and microbiome- data frameworks. In addition, its involvement in
immune interactions in African cancer cohorts. These the National Comprehensive Cancer Research
approaches support biomarker discovery, molecular Consortium (NCCRC) contributes to shared
characterisation, and risk stratification.
platforms that integrate precision oncology,
AI is also being applied in the clinical and translational molecular diagnostics, and AI-enabled technologies
research domain. This is demonstrated by PORU's to address South Africa's growing cancer burden.

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