Nandi Siegfried is a Chief Specialist Scientist based part-time in the Mental Health, Alcohol, Substance Use and Tobacco Research Unit of the South African Medical Research Council.

She has a medical degree from the University of Cape Town and an MPH (Hons) from the University of Sydney, Australia. She holds a specialist Fellowship in the College of Public Health Medicine and was a Nuffield Medical Fellow at the University of Oxford from 2004 to 2007, where she obtained a DPhil in Clinical Epidemiology.

Her research expertise includes systematic review methodology, the conduct and quality of clinical trials, and using evidence to inform clinical guidelines and policy, primarily in the HIV/AIDS and alcohol and other drug fields. Her work in MAST-RU focuses on ensuring methodological rigour and promoting interventional research.

She established and leads the MAST-RU monthly journal club which aims to instil awareness of bias in research and encourage critical appraisal skills among our staff.

In addition to her MAST-RU work, she consults independently in the public health space, including contributing as technical adviser, chair, and methodological facilitator to over 20 World Health Organization Guidelines Development Groups. She currently holds an honorary Associate Professorship at the University of Cape Town.