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Supports decision-making in health and social policy to strengthen health systems to achieve universal health coverage

Health Systems

The Health Systems Research Unit (HSRU) is committed to building stronger health and social-care systems in South Africa, Africa and globally through collaborative health-policy and systems research that promotes equity and transformation. Our research contributes to national, regional and international evidence-informed health and social policy decision-making and health systems with the aim of advancing Universal Health Coverage and Primary Health Care.  This involves multidisciplinary, intersectoral research across several areas of the health system (private-public sector, health facilities, schools, community) and along the life course. We have teams leading work with vulnerable populations – newborn, maternal and child health; sexual reproductive health; and in specific disciplines including social policy; health economics; evidence synthesis and knowledge translation.

We work in five thematic areas:

  • Maternal, Newborn and Child Health: Understanding health system requirements for the optimal delivery of community and primary care services for women, newborns, and children
  • Social Protection for Child Health: Strengthening social protection interventions and policies to promote health and well-being of children and their caregivers
  • Health of Adolescents and Young People: Promoting universal health coverage for the sexual, reproductive and mental health and well-being of adolescents, their caregivers and young people
  • Health Economics: Using health economics analytic tools to contribute to decision-making about investments in health systems (including investments in human resources and health programmes, interventions and services)
  • Evidence Synthesis: Supporting evidence-informed decision making and learning health systems, and informing future research, through providing synthesized evidence and supporting the translation of this knowledge


We have expertise in a range of study designs, methodologies, and processes including:

  • Cluster randomised controlled trials
  • Process evaluations
  • National surveillance / national impact evaluations
  • Operations research
  • Analysis of survey data using epidemiological techniques
  • Systematic reviews of qualitative and quantitative evidence, and knowledge translation
  • Economic evaluations and human resource planning
  • Qualitative research
  • Heath systems and other policy and guideline development
  • Respondent-driven surveillance methods
  • Simulated client assessments
  • Visual participatory methods
  • Evaluations of mHealth interventions
  • Knowledge translation