Professor Johnny Mahlangu

Profession & Current Position
Clinical Haematologist
Head of School of Pathology, University of the Witwatersrand and NHLS

Area of Expertise
Therapeutic innovations/translational research in haemostasis

Qualifications & Designation/s

  • 2008 - MMed(Haem):  University of the Witwatersrand, Johannesburg
  • 2002 - Cert Clin Haem (SA):  Colleges of Medicine of South Africa - subspecialist
  • 1999 - FCPath (SA)(Haem):  Colleges of Medicine of South Africa - specialist
  • 1994 - MBBCh:  University of the Witwatersrand, Johannesburg
  • 1988 - BSc (Lab Med):  University of the Witwatersrand, Johannesburg

Awards

  • American Society of Haematology Global Capacity Building Award (2019)
  • University of the Witwatersrand Faculty Health Sciences Research Achievement award (2019)
  • University of the Witwatersrand Vice Chancellor Academic Citizenship award (2018)
  • South African National Research Foundation B rating (2018)
  • Novo Nordisk Haemophilia Foundation International Haemophilia Community Award (2018)
  • Faculty of Health Sciences Honors Celebration Special recognition (2018)
  • Colleges of Medicine of South Africa Triennium Service Recognition Certificate (2018)
  • Fellow of the Academy of Medicine of Malaysia (2018)
  • University of the Witwatersrand Faculty Research Day Best Oral Presentation (2018)
  • International Society of Haemostasis and Thrombosis SSC top rated poster presentation (2018)
  • University of the Witwatersrand Faculty Health Sciences Research Achievement award (2018)
  • Publons International Top Peer reviewer award (2017)
  • University of the Witwatersrand Faculty Health Sciences Research Achievement award (2017)
  • Elected American Society of Hematology member (2017)
  • National Health Laboratory Service 20-year Service Award (2016)
  • University of the Witwatersrand Faculty Health Sciences Research Achievement award (2016)
  • Fellowship: Management and Leadership of Higher Education South Africa (2015)
  • Fellowship: Southern African Society of Haemostasis and Thrombosis (2008)
  • Fellowship: University of the Witwatersrand Arthur Robertson in Haemophilia (2003) 
  • South African Medical Research Council Postgraduate Merit award (1999)
  • South African Medical Research Council Postgraduate Merit award (2000)
  •  University of the Witwatersrand Postgraduate Merit Award (1999)

Top Publications

  • Johnny Mahlangu. Emicizumab for prevention of bleeds in Haemophilia. Expert Biological Therapies 2019 Jun 13:1-9
  • Johnny Mahlangu, Johannes Oldenburg, Ido Paz-Priel, Claude Negrier, Markus Niggli, Maria Elisa Mancuso, Christophe Schmitt, Victor-Jiménez Yuste, Christine Kempton, Christophe Dhalluin, Michael Callaghan, Willen Bujan, Midori Shima, Elina Asikanius, Gallia G. Levy, Rebecca Kruse-Jarres- Emicizumab Prophylaxis in Hemophilia A without Inhibitors- Study NEJM 2018, 379(9): 811-22
  • Oldenburg J, Mahlangu J N, Kim B, Schmitt C, Callaghan M, Young G, Santagostino E, Kruse-Jarres R, Claude Negrier, Kessler C, Valente N, Asikanius E, Levy GG, Windyga J, Shima M. Emicizumab Prophylaxis in Hemophilia A with Inhibitors N Engl J Med 2017; 377:809-18
  • Kathelijn Fischer, Roshni Kulkarni, Beatrice Nolan, Johnny Mahlangu, Savita Rangarajan, Giulia Gambino, Lei Diao, Lynda M Cristiano, Glenn F Pierce, Geoff Allen Recombinant factor IX Fc fusion protein in children with hemophilia B: results of phase 3 multicenter Kids B-LONG study. Lancet Haematology 2017; 4: e75-e82
  • Flora Peyvandi, MD PhD, Pier Mannuccio Mannucci, MD, Isabella Garagiola, PhD, Mohsen Elalfy, MD, Amal El-Beshlawy, MD, Madatha V. Ramanan, MD, Peyman Eshghi, MD, Suresh Hanagavadi,Ramabadran Varadarajan, MD, Mehran Karimi, MD, Mamta V. Manglani, MD, Cecil Ross, MD, Guy Young, MD, Tulika Seth, MD,Shashikant Apte, MD FRCPA, Dinesh M. Nayak, MD, Adriana C. Sandoval Gonzales, MD, Elena Santagostino, MD PhD, Maria Elisa Mancuso, MD PhD, Johnny N. Mahlangu, MD, Santiago Bonanad, PhD, Monica Cerqueira, MD, Nadia P. Ewing, MD, Christoph Male, MD MSC, Tarek Owaidah, MD FRCPA Veronica Soto Arellano, MD, Nathan L. Kobrinsky, MD FRCP, Suvankar Majumdar, MD, Rosario Perez Garrido, MD, Anupam Sachdeva, Mindy Simpson, MD FAAP, Mathew Thomas, Ezio Zanon, MD, ALI Bulent Antmen, Kaan Kavakli, MD Marilyn Manco-Johnson, MD Monica Martinez, MD, Esperanza Marzouka, MS, PS,Maria Gabriella Mazzucconi, MD, Daniela Neme, MD, Angeles Palomo Bravo, MD,Rogelio Paredes Aguilera, MD, Alessandra Nunes Loureiro Prezotti, MD,Source of Factor VIII Replacement (PLASMATIC OR RECOMBINANT) and Incidence of Inhibitory Alloantibodies in Previously Untreated Patients with Severe Hemophilia a: The Multicenter Randomized Sippet Study NEJM 2016;374:2054-64.
  • Johnny Mahlangu, Jerry S. Powell, Margaret V. Ragni, Pratima Chowdary, Neil C. Josephson, Ingrid, Pabinger, Hideji Hanabusa, Naresh Gupta, Roshni Kulkarni, Patrick Fogarty, David Perry, Amy Shapiro, K. John Pasi, Shashikant Apte, Ivan Nestorov, Haiyan Jiang, Shuanglian Li, Srividya Neelakantan, Lynda, M. Cristiano, Jaya Goyal, Jurg M. Sommer, Jennifer A. Dumont, Nigel Dodd, Karen Nugent, Gloria, Vigliani, Alvin Luk, Aoife Brennan and Glenn F. Pierce. Phase 3 study of recombinant factor VIII Fc fusion protein in severe hemophilia.  Blood. 2014 Jan 16;123(3):317-25.

Featured in the Media

  • 2019/07/08: ISTH TV interview on novel therapies, Melbourne, Australia
  • 2019/05/20: Chai FM radio interview on haemophilia, Johannesburg
  • 2019/04/17: SABC TV interview in World haemophilia Day, Johannesburg
  • 2018/07/20: Medscape online education session on Gene Therapy in haemophilia
  • 2018/05/23: International Media and analyst symposium on Haven 3 study, Glasgow
  • 2018/05/21: Swiss Broadcasting Corporation Interview on haemophilia, Glasgow
  • 2018/04/17: MIxFM interview on haemophilia
  • 2018/04/16: ABC radio interview on haemophilia
  • 2018/04/16: Mauritian television interview on haemophilia
  • 2018/04/12: eNCA life style interview on haemophilia
  • 2017/04/17: eNEWS interview on haemophilia
  • 2016/12/16: ISTH/WFH Webinar on prophylaxis in developing countries
  • 2016/10/25: Webex presentation on Single Chain recombinant FVIII
  • 2016/04/14: ITV Network Interview on haemophilia
  • 2015/07/31: Canadian Haemophilia Society Interview on rFVIIIFc
  • 2015/04/17: SABC 1 TV Interview on Haemophilia
  • 2015/04/17: Media release on Haemophilia for World Haemophilia Day
  • 2015/04/16: Metro FM interview on haemophilia
  • 2015/03/31: SAFM Interview on haemophilia
  • 2015/02/18: Media Interview on Haemophilia (Marion Sher)

Association to the SAMRC
Chair and board member of SAMRC; SAMRC postgraduate merit bursary

Position: 
CHAIRPERSON