Biomedical Research and Innovation Platform

• The Group’s longstanding innovative research on early changes leading to Type 2 Diabetes (T2D) has resulted in the discovery and characterisation of previously unreported pathological changes related to the very early stages of development of the disease, prior to raised blood sugar levels.  The Group is currently investigating their potential as very early markers of people at risk of developing T2D.  These markers will be able to identify the risk of developing T2D at a much earlier stage than any other marker available to date, allowing significantly earlier intervention and treatment and, hopefully, prevent the secondary effects of T2D which affects both the quality of life and leads to the early death of people.

• The group has also established and characterised several animal models for further research, including an insulin resistant rat model for typical symptoms of early-stage type-2 diabetes, a streptozotocin model typical of type-1 diabetes and a triglyceride model representing the ‘metabolic syndrome’ (Syndrome X) patient who is at risk of developing type-2 diabetes. These models enable in depth research of type-2 diabetes and type-1 diabetes.  Particularly how the disease develops, what external factors induce and/or promote the disease and the process by which this occurs.

• Many plants of Southern African or African origin have been claimed to have anti-diabetic properties. The group’s investigations have already been successful in identifying two plants for their efficacy in treating aspects of the broader metabolic syndrome.

The 55^th SEMDSA Congress was held this past weekend, 8-11 September 2022 and a few of our colleagues and students had the pleasure and opportunity of attending and presenting their work and studies.

We Acknowledge and Congratulate two of our colleagues who received Awards for the work they do; and because of them, BRIP received 5 awards!

Huge Congratulations to YOU BOTH.

@Tarryn Willmer  SAMRC

• Travel Award
• Endocrine Publication Award (Basic Sciences)
• Best Poster award (Basic Sciences)

@Julia Goedecke  SAMRC

• Diabetes Publication Award (Clinical)
• Diabetes Publication Award (Basic Sciences)  - Award to Amy Mendham (Julia’s postdoc)

The Chan Soon-Shiong Family Foundation (CSSFF) and the South African Medical Research Council (SAMRC) have announced a five-year collaboration to initiate a skills development programme that aims to train a cohort of young African candidates to build a skilled workforce to manufacture vaccines on the African continent. This Programme will be achieved through a mixture of virtual, online, in-person lectures and, most importantly, hands-on lab-based training by awarding Studentships, Scholarships and Fellowships in vaccine-related disciplines in the health, life and allied sciences.

Link to RFA on the Website

https://www.samrc.ac.za/request-for-applications/chan-soon-shiong-family-foundation-cssff-and-south-african-medical-research

The South African Medical Research Council participates in the Global Alliance for Chronic Diseases, a collaboration of major international research funding agencies that support joint funding calls and research capacity building activities to address chronic, non-communicable diseases. The alliance focuses on implementation research in low- and middle- income countries (LMICs) and in vulnerable and indigenous populations in high-income countries (HICs).

The GACD have announced the launch of the Implementation Science e-Hub. The e-Hub is a free, virtual platform for knowledge and skill development in implementation research. It is intended for researchers, students, policymakers and practitioners at any stage in their career, from anywhere in the world, interested in improving their knowledge of implementation research, especially its application for the prevention and management of non-communicable diseases in low-resource settings.

For further information, visit https://gacd.org/research/implementation-science-capacity-building/implementation-science-e-hub 

• 12th Annual BRIP Symposium Save the date
• 12th Annual BRIP Symposium abstract guidelines

• Save the Date Invitation
• 11th BRIP Symposium Scientific Programme & Abstract booklet
• ePoster Book

• Programme & Abstract Book
• ePoster Book
• Prize Giving

On Sunday the 28th August, Dr Kwazi Gabuza, senior Scientist at the Biomedical Research Innovation Platform, took part and completed his second Comrades marathon.

The Comrades Marathon is an ultramarathon of approximately 89 km, which is run annually in the KwaZulu-Natal province and is said to be the world's largest and oldest ultramarathon race. The race takes place between the cities of Durban and Pietermaritzburg, with the direction of the race alternating each year between the "up" run (87 km) starting from Durban and the "down" run (now 90.184 km) starting from Pietermaritzburg. The race had been postponed in 2020 and 2021 due to the COVID pandemic.

Completed the race for the 3rd time in a race-time of 10:52:59, Dr Gabuza said "It was uncertain that the Comrades would take place this year, following the two year break and the restrictions that were only scraped early this year. Only in March was everyone made aware that it will be happening in 2022.

My training then started with the hope to be fully fit by 28 August. The two-year break definitely took its toll on the runners. It was a very challenging Comrades marathon, much harder than my previous attempts in 2017 and 2019.”

Well done Kwazi and congratulations on finishing yet another Comrades marathon. Here’s to many more to come