The Centre for the Study of Antimicrobial Resistance (CAMRA) consists of a multi-disciplinary team of national and international experts focused on addressing specific aspects of bacterial multi-drug resistant pathogens, including tuberculosis.
Key focus areas
- To better understand the pathogenesis of drug resistance by studying pharmacokinetic mismatch i.e. drug gradients and its relationship to minimum inhibitory drug concentrations across lung cavities and bacterial abscesses/collections in TB and non-TB MDR infections.
- To evaluate signal amplification methods as diagnostic tools to detect micro hetero-resistance (rare populations of drug resistant bacteria) in sputum, tracheal aspirates and blood compared to the site of disease i.e. lung parenchyma, cavities, abscesses/fluid collections in TB and non-TB MDR infections.
- To conduct preliminary studies to determine the levels and efficacy of adjunct inhaled antibiotics at the disease sitein TB and MDR bacterial pneumonia, and to develop and test inhaled formulations for future animal and human studies.
Unit Director: Prof Keertan Dheda
|For more information, visit the Centre for the Study of Antimicrobial Resistance (CAMRA) website|