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Centre for the Study of Antimicrobial Resistance

Current Projects

  • Determination of resistance profile and measurement of second line TB drug PK levels in TB cavities from explanted lungs of drug-resistant TB patients undergoing surgery.
  • Measurement of drug levels in exhaled breath of TB patients.
  • Detection of micro-heteroresistant TB bacteria populations in sputum from drug resistant TB patients and their relation to resistance profiles in samples collected from TB cavities
  • Inhaled antibiotics – development of clofazimine inhaled dry powder formulation