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Antiviral Gene Therapy

Current Projects

  • Engineering epigenetic HBV DNA modifiers containing DNA methyl transferases.
  • Synthesis of chemically modified mRNA for use in treatment of chronic HBV infection.
  • Next generation sequencing methods for the detection of off-target mutation by anti-HBV gene editors.
  • Engineering of self-replicating anti-HBV mRNA vaccines.
  • Incorporation of therapeutic nucleic acids into non-viral vectors comprising cyclodextrin conjugates with liver-targeting moieties.